Set against a back-drop of wondrous landscapes and even stranger characters, The Mouse and The Monster is the story about the unlikeliest of pals, an 8 foot tall, one-eyed shocking blue monster named Mo and his little buddy, Chesbro Mouse. Mo, with half the brain of a goofy beatnik and half of a frantic, unstable lunatic, operates on the hilarious fringe of utter madness, while Chesbro, Mr. Conservative in his little red coat and tie, does his best to keep the two of them out of trouble and out of the clutches of Mo's laughably evil creator, the mad Doctor Wankerstein.

Doctor W, by day the sadistic town pediatrician, by night, a mad scientist extraordinaire along with his oblique wife, Olga, a performance artist from Berlin (whom he constantly refers to as "Igor"), are in hot pursuit of Mo and Chesbro. Chesbro, having learned of Doctor W's evil scheme to replace Mo's gray matter with the brain of Doc's favorite dead pianist, Liberace, freed Mo from the demented doctor's laboratory just in the knick of time. They're on the lam with Doc and Olga just a step behind.

From their awkward attempts at trying to assimilate into urban life, to high seas and other-worldly adventures, Mo and chesbro are side by side, buddy and buddy, trying to make their way through life.

Airing every Saturday & Sunday at 1:30 p.m. on the new Fox Family Channel. Check your local listings.